K101N (p.Lys101Asn) variant of CDH2 (Cadherin-2)
K101N (p.Lys101Asn) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K101N (p.Lys101Asn) variant details
- p.Lys101Asn
- TOPMed rs1404361272
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.02
- CADD 19.20
- PolyPhen-2 0.04
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available