D108Y (p.Asp108Tyr) variant of CDH2 (Cadherin-2)
D108Y (p.Asp108Tyr) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
D108Y (p.Asp108Tyr) variant details
- p.Asp108Tyr
- ExAC rs751296292
- gnomAD rs751296292
- Missense
- Variant Prioritization Score for Impact Estimate 0.79
- REVEL 0.83
- MetaLR 0.68
- MetaSVM 0.43
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available