A106T (p.Ala106Thr) variant of CDH2 (Cadherin-2)
A106T (p.Ala106Thr) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
A106T (p.Ala106Thr) variant details
- p.Ala106Thr
- cosmic curated COSV52272
- gnomAD rs1469377111
- Missense
- Variant Prioritization Score for Impact Estimate 0.642
- REVEL 0.60
- MetaLR 0.58
- MetaSVM 0.07
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available