W6C (p.Trp6Cys) variant of CD8B (P10966)
W6C (p.Trp6Cys) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
W6C (p.Trp6Cys) variant details
- p.Trp6Cys
- ExAC rs767490181
- TOPMed rs767490181
- gnomAD rs767490181
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.17
- MetaLR 0.14
- MetaSVM -0.74
- CADD 22.70
- PolyPhen-2 0.02
- SIFT 0.03
- Population evidence available
- Structural context available