V37A (p.Val37Ala) variant of CD8B (P10966)
V37A (p.Val37Ala) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V37A (p.Val37Ala) variant details
- p.Val37Ala
- ExAC rs758188273
- TOPMed rs758188273
- gnomAD rs758188273
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.21
- MetaLR 0.15
- MetaSVM -0.95
- CADD 0.05
- PolyPhen-2 0.01
- SIFT 0.58
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available