V21L (p.Val21Leu) variant of CD8B (P10966)
V21L (p.Val21Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V21L (p.Val21Leu) variant details
- p.Val21Leu
- TOPMed rs1676396524
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.12
- MetaLR 0.19
- MetaSVM -0.88
- CADD 8.23
- PolyPhen-2 0.03
- SIFT 0.39
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available