V15L (p.Val15Leu) variant of CD8B (P10966)
V15L (p.Val15Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- gnomAD rs1281715212
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.06
- CADD 24.60
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00033)
- Structural context available