V106M (p.Val106Met) variant of CD8B (P10966)
V106M (p.Val106Met) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
V106M (p.Val106Met) variant details
- p.Val106Met
- 1000Genomes rs367817222
- ESP rs367817222
- ExAC rs367817222
- TOPMed rs367817222
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.29
- MetaLR 0.45
- MetaSVM -0.45
- CADD 13.90
- PolyPhen-2 0.75
- SIFT 0.03
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available