V106L (p.Val106Leu) variant of CD8B (P10966)
V106L (p.Val106Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V106L (p.Val106Leu) variant details
- p.Val106Leu
- 1000Genomes rs367817222
- ESP rs367817222
- ExAC rs367817222
- TOPMed rs367817222
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.07
- MetaLR 0.13
- MetaSVM -1.01
- CADD 4.39
- PolyPhen-2 0.06
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available