T125N (p.Thr125Asn) variant of CD8B (P10966)
T125N (p.Thr125Asn) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T125N (p.Thr125Asn) variant details
- p.Thr125Asn
- ExAC rs755741417
- TOPMed rs755741417
- gnomAD rs755741417
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.14
- MetaLR 0.35
- MetaSVM -0.70
- CADD 0.43
- PolyPhen-2 0.76
- SIFT 0.08
- Most common in the HGDP:BALOCHI population (allele frequency 0.022)
- Structural context available