T125I (p.Thr125Ile) variant of CD8B (P10966)
T125I (p.Thr125Ile) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T125I (p.Thr125Ile) variant details
- p.Thr125Ile
- ExAC rs755741417
- TOPMed rs755741417
- gnomAD rs755741417
- Missense
- Variant Prioritization Score for Impact Estimate 0.081
- REVEL 0.04
- MetaLR 0.13
- MetaSVM -0.97
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 0.47
- Population evidence available
- Structural context available