S65N (p.Ser65Asn) variant of CD8B (P10966)
S65N (p.Ser65Asn) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S65N (p.Ser65Asn) variant details
- p.Ser65Asn
- gnomAD rs1189628254
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.13
- MetaLR 0.29
- MetaSVM -0.74
- CADD 11.30
- PolyPhen-2 0.41
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available