S62R (p.Ser62Arg) variant of CD8B (P10966)
S62R (p.Ser62Arg) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S62R (p.Ser62Arg) variant details
- p.Ser62Arg
- ExAC rs746956335
- gnomAD rs746956335
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.19
- MetaLR 0.28
- MetaSVM -0.81
- CADD 20.50
- PolyPhen-2 0.94
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available