S20A (p.Ser20Ala) variant of CD8B (P10966)
S20A (p.Ser20Ala) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S20A (p.Ser20Ala) variant details
- p.Ser20Ala
- TOPMed rs1350377646
- gnomAD rs1350377646
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.16
- MetaLR 0.27
- MetaSVM -0.86
- CADD 2.76
- PolyPhen-2 0.37
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 2e-05)
- Structural context available