S133N (p.Ser133Asn) variant of CD8B (P10966)
S133N (p.Ser133Asn) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S133N (p.Ser133Asn) variant details
- p.Ser133Asn
- ExAC rs758724392
- gnomAD rs758724392
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.08
- MetaLR 0.18
- MetaSVM -0.82
- CADD 2.50
- PolyPhen-2 0.13
- SIFT 0.30
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available