S105R (p.Ser105Arg) variant of CD8B (P10966)
S105R (p.Ser105Arg) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S105R (p.Ser105Arg) variant details
- p.Ser105Arg
- ExAC rs764433373
- TOPMed rs764433373
- gnomAD rs764433373
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.08
- MetaLR 0.08
- MetaSVM -1.03
- CADD 0.00
- PolyPhen-2 0.02
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available