R58L (p.Arg58Leu) variant of CD8B (P10966)
R58L (p.Arg58Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R58L (p.Arg58Leu) variant details
- p.Arg58Leu
- cosmic curated COSV58926
- 1000Genomes rs184840038
- ExAC rs184840038
- TOPMed rs184840038
- Missense
- Variant Prioritization Score for Impact Estimate 0.0994
- REVEL 0.07
- MetaLR 0.14
- MetaSVM -0.97
- CADD 0.93
- PolyPhen-2 0.01
- SIFT 0.57
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available