R58H (p.Arg58His) variant of CD8B (P10966)
R58H (p.Arg58His) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
R58H (p.Arg58His) variant details
- p.Arg58His
- 1000Genomes rs184840038
- ExAC rs184840038
- TOPMed rs184840038
- gnomAD rs184840038
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.17
- MetaLR 0.30
- MetaSVM -0.75
- CADD 1.65
- PolyPhen-2 0.13
- SIFT 0.50
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available