R51S (p.Arg51Ser) variant of CD8B (P10966)
R51S (p.Arg51Ser) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R51S (p.Arg51Ser) variant details
- p.Arg51Ser
- 1000Genomes rs11558603
- ExAC rs11558603
- gnomAD rs11558603
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.06
- MetaLR 0.10
- MetaSVM -1.00
- CADD 5.97
- PolyPhen-2 0.14
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available