R51C (p.Arg51Cys) variant of CD8B (P10966)
R51C (p.Arg51Cys) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R51C (p.Arg51Cys) variant details
- p.Arg51Cys
- 1000Genomes rs11558603
- ExAC rs11558603
- gnomAD rs11558603
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.21
- MetaLR 0.20
- MetaSVM -0.79
- CADD 17.10
- PolyPhen-2 0.95
- SIFT 0.05
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available