R2W (p.Arg2Trp) variant of CD8B (P10966)
R2W (p.Arg2Trp) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R2W (p.Arg2Trp) variant details
- p.Arg2Trp
- Ensembl rs1274868984
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.09
- MetaLR 0.16
- MetaSVM -1.00
- CADD 25.30
- PolyPhen-2 0.35
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available