R2Q (p.Arg2Gln) variant of CD8B (P10966)
R2Q (p.Arg2Gln) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
R2Q (p.Arg2Gln) variant details
- p.Arg2Gln
- TOPMed rs1676623026
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.98
- CADD 11.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Ashkenazi Jewish population (allele frequency 6.4e-05)
- Structural context available