P61L (p.Pro61Leu) variant of CD8B (P10966)
P61L (p.Pro61Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
P61L (p.Pro61Leu) variant details
- p.Pro61Leu
- 1000Genomes rs140127269
- ESP rs140127269
- ExAC rs140127269
- TOPMed rs140127269
- Missense
- Variant Prioritization Score for Impact Estimate 0.0883
- REVEL 0.03
- MetaLR 0.03
- MetaSVM -1.07
- CADD 5.77
- PolyPhen-2 0.12
- SIFT 0.22
- Most common in the 1KG:MSL population (allele frequency 0.044)
- Structural context available