P3R (p.Pro3Arg) variant of CD8B (P10966)
P3R (p.Pro3Arg) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P3R (p.Pro3Arg) variant details
- p.Pro3Arg
- Ensembl rs1027597679
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.06
- MetaLR 0.22
- MetaSVM -0.92
- CADD 21.20
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the East Asian population (allele frequency 7.5e-05)
- Structural context available