P3L (p.Pro3Leu) variant of CD8B (P10966)
P3L (p.Pro3Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P3L (p.Pro3Leu) variant details
- p.Pro3Leu
- Ensembl rs1027597679
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.92
- CADD 17.40
- PolyPhen-2 0.99
- SIFT 0.68
- Most common in the African/African-American population (allele frequency 4.3e-05)
- Structural context available