P108L (p.Pro108Leu) variant of CD8B (P10966)
P108L (p.Pro108Leu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P108L (p.Pro108Leu) variant details
- p.Pro108Leu
- TOPMed rs1393805545
- gnomAD rs1393805545
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -0.93
- CADD 8.04
- PolyPhen-2 0.06
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 9.7e-05)
- Structural context available