L9S (p.Leu9Ser) variant of CD8B (P10966)
L9S (p.Leu9Ser) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L9S (p.Leu9Ser) variant details
- p.Leu9Ser
- ExAC rs751398411
- gnomAD rs751398411
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.24
- MetaLR 0.20
- MetaSVM -0.95
- CADD 24.40
- PolyPhen-2 0.48
- SIFT 0.09
- Most common in the South Asian population (allele frequency 3e-05)
- Structural context available