L8F (p.Leu8Phe) variant of CD8B (P10966)
L8F (p.Leu8Phe) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L8F (p.Leu8Phe) variant details
- p.Leu8Phe
- gnomAD rs1446657426
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.28
- MetaLR 0.27
- MetaSVM -0.92
- CADD 22.10
- PolyPhen-2 0.89
- SIFT 0.30
- Population evidence available
- Structural context available