L7F (p.Leu7Phe) variant of CD8B (P10966)
L7F (p.Leu7Phe) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- gnomAD rs1167021963
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.12
- MetaLR 0.27
- MetaSVM -0.84
- CADD 22.30
- PolyPhen-2 0.99
- SIFT 1.00
- Most common in the South Asian population (allele frequency 3e-05)
- Structural context available