L39V (p.Leu39Val) variant of CD8B (P10966)
L39V (p.Leu39Val) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L39V (p.Leu39Val) variant details
- p.Leu39Val
- ExAC rs752375575
- gnomAD rs752375575
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.45
- MetaLR 0.43
- MetaSVM -0.48
- CADD 3.29
- PolyPhen-2 0.33
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available