K77E (p.Lys77Glu) variant of CD8B (P10966)
K77E (p.Lys77Glu) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
K77E (p.Lys77Glu) variant details
- p.Lys77Glu
- gnomAD rs1397756224
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.12
- MetaLR 0.27
- MetaSVM -0.77
- CADD 13.40
- PolyPhen-2 0.56
- SIFT 0.08
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available