K128Q (p.Lys128Gln) variant of CD8B (P10966)
K128Q (p.Lys128Gln) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K128Q (p.Lys128Gln) variant details
- p.Lys128Gln
- ExAC rs780567812
- gnomAD rs780567812
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.12
- MetaLR 0.17
- MetaSVM -0.96
- CADD 15.50
- PolyPhen-2 0.48
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available