K107R (p.Lys107Arg) variant of CD8B (P10966)
K107R (p.Lys107Arg) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K107R (p.Lys107Arg) variant details
- p.Lys107Arg
- ExAC rs775661607
- TOPMed rs775661607
- gnomAD rs775661607
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.15
- MetaLR 0.29
- MetaSVM -0.78
- CADD 15.50
- PolyPhen-2 0.54
- SIFT 0.08
- Most common in the HGDP:HAN population (allele frequency 0.015)
- Structural context available