I90T (p.Ile90Thr) variant of CD8B (P10966)
I90T (p.Ile90Thr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
I90T (p.Ile90Thr) variant details
- p.Ile90Thr
- TOPMed rs1424922092
- gnomAD rs1424922092
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.20
- MetaLR 0.23
- MetaSVM -0.73
- CADD 18.80
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available