I113V (p.Ile113Val) variant of CD8B (P10966)
I113V (p.Ile113Val) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I113V (p.Ile113Val) variant details
- p.Ile113Val
- TOPMed rs1368246577
- gnomAD rs1368246577
- Missense
- Variant Prioritization Score for Impact Estimate 0.0891
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.00
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available