I113F (p.Ile113Phe) variant of CD8B (P10966)
I113F (p.Ile113Phe) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
I113F (p.Ile113Phe) variant details
- p.Ile113Phe
- TOPMed rs1368246577
- gnomAD rs1368246577
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -1.05
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available