I100F (p.Ile100Phe) variant of CD8B (P10966)
I100F (p.Ile100Phe) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I100F (p.Ile100Phe) variant details
- p.Ile100Phe
- ExAC rs751852075
- TOPMed rs751852075
- gnomAD rs751852075
- Missense
- Variant Prioritization Score for Impact Estimate 0.0909
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.02
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 0.79
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available