H67Y (p.His67Tyr) variant of CD8B (P10966)
H67Y (p.His67Tyr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
H67Y (p.His67Tyr) variant details
- p.His67Tyr
- cosmic curated COSV58926
- ExAC rs758184342
- TOPMed rs758184342
- gnomAD rs758184342
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.08
- MetaLR 0.09
- MetaSVM -0.98
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available