H17Q (p.His17Gln) variant of CD8B (P10966)
H17Q (p.His17Gln) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
H17Q (p.His17Gln) variant details
- p.His17Gln
- cosmic curated COSV10523
- 1000Genomes rs137953763
- ESP rs137953763
- ExAC rs137953763
- Missense
- Variant Prioritization Score for Impact Estimate 0.0761
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -0.98
- CADD 0.07
- PolyPhen-2 0.07
- SIFT 0.43
- Most common in the HGDP:ADYGEI population (allele frequency 0.029)
- Structural context available