G82R (p.Gly82Arg) variant of CD8B (P10966)
G82R (p.Gly82Arg) in CD8B (P10966) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G82R (p.Gly82Arg) variant details
- p.Gly82Arg
- NCI-TCGA Cosmic COSV1005
- cosmic curated COSV10051
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.17
- MetaLR 0.37
- MetaSVM -0.67
- CADD 16.40
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available