G18S (p.Gly18Ser) variant of CD8B (P10966)
G18S (p.Gly18Ser) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G18S (p.Gly18Ser) variant details
- p.Gly18Ser
- TOPMed rs1229601797
- gnomAD rs1229601797
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.14
- MetaLR 0.11
- MetaSVM -1.03
- CADD 9.54
- PolyPhen-2 0.51
- SIFT 0.43
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available