E88K (p.Glu88Lys) variant of CD8B (P10966)
E88K (p.Glu88Lys) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
E88K (p.Glu88Lys) variant details
- p.Glu88Lys
- cosmic curated COSV10523
- TOPMed rs1192831331
- gnomAD rs1192831331
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.06
- MetaLR 0.13
- MetaSVM -1.02
- CADD 1.78
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available