E86D (p.Glu86Asp) variant of CD8B (P10966)
E86D (p.Glu86Asp) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
E86D (p.Glu86Asp) variant details
- p.Glu86Asp
- TOPMed rs896939012
- gnomAD rs896939012
- Missense
- Variant Prioritization Score for Impact Estimate 0.0711
- REVEL 0.02
- MetaLR 0.10
- MetaSVM -0.99
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available