E68K (p.Glu68Lys) variant of CD8B (P10966)
E68K (p.Glu68Lys) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
E68K (p.Glu68Lys) variant details
- p.Glu68Lys
- 1000Genomes rs576844921
- ExAC rs576844921
- TOPMed rs576844921
- gnomAD rs576844921
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.37
- MetaLR 0.40
- MetaSVM -0.28
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the 1KG:ACB population (allele frequency 0.0054)
- Structural context available