E109G (p.Glu109Gly) variant of CD8B (P10966)
E109G (p.Glu109Gly) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
E109G (p.Glu109Gly) variant details
- p.Glu109Gly
- ExAC rs765411219
- gnomAD rs765411219
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.17
- MetaLR 0.26
- MetaSVM -0.79
- CADD 11.00
- PolyPhen-2 0.10
- SIFT 0.23
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available