D110N (p.Asp110Asn) variant of CD8B (P10966)
D110N (p.Asp110Asn) in CD8B (P10966) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
D110N (p.Asp110Asn) variant details
- p.Asp110Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.63
- MetaLR 0.82
- MetaSVM 0.85
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available