C41Y (p.Cys41Tyr) variant of CD8B (P10966)
C41Y (p.Cys41Tyr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
C41Y (p.Cys41Tyr) variant details
- p.Cys41Tyr
- gnomAD rs1487289172
- Missense
- Variant Prioritization Score for Impact Estimate 0.716
- REVEL 0.68
- MetaLR 0.72
- MetaSVM 0.61
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available