C41S (p.Cys41Ser) variant of CD8B (P10966)
C41S (p.Cys41Ser) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
C41S (p.Cys41Ser) variant details
- p.Cys41Ser
- gnomAD rs1190328641
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.71
- MetaLR 0.70
- MetaSVM 0.53
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available