C116Y (p.Cys116Tyr) variant of CD8B (P10966)
C116Y (p.Cys116Tyr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
C116Y (p.Cys116Tyr) variant details
- p.Cys116Tyr
- cosmic curated COSV10605
- Missense
- Variant Prioritization Score for Impact Estimate 0.789
- REVEL 0.81
- MetaLR 0.72
- MetaSVM 0.65
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available