A43T (p.Ala43Thr) variant of CD8B (P10966)
A43T (p.Ala43Thr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A43T (p.Ala43Thr) variant details
- p.Ala43Thr
- TOPMed rs1277076160
- gnomAD rs1277076160
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.10
- MetaLR 0.17
- MetaSVM -0.87
- CADD 0.02
- PolyPhen-2 0.08
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available